Polynucleotides are purified DNA fragments derived from fish. They are highly compatible with human DNA, making them one of the most effective and natural treatments for skin regeneration.
As we age, skin damage from sun exposure, pollution, and stress slows down our body’s natural repair processes. Polynucleotides trigger a powerful healing response—revitalising damaged cells, repairing DNA, and improving fibroblast activity (the cells responsible for skin structure and elasticity). This boosts collagen production, enhances skin health, and helps the skin function as if it were years younger.
Back to Facial Aesthetics
Polynucleotide treatments can help improve:
Polynucleotides can be used anywhere on the skin, with popular areas including:
A course of 3 treatments, spaced 2–3 weeks apart, is recommended. To maintain results, a top-up every 6 months is advised.
Comfort
A topical numbing cream is applied before treatment. Some mild stinging may occur, but most clients find the procedure very tolerable.
Our Product
We use Plinest® Polynucleotides-HPT® by Mastelli, a trusted brand with over 70 years of research and medical use. Their highly purified formula ensures safety and minimal risk of allergic reaction.
Real stories from happy smiles, hear how we’ve made a difference.
View our testimonials
“Above and beyond, thank you.”
“Always been looked after well here, Amy is a brilliant dentist, and the...”
“Always good, friendly service from every member of staff. The dentist herself is...”
“Friendly staff and helpful advice.”
“Always a great service and always friendly people.”
“Always so helpful, friendly and efficient! Top-class service in every way. Outstanding.”
“Staff are always friendly, and I have received great treatment every time from...”
“As always, friendly, helpful and a pleasure to visit.”
“Great dental practice. I have been a patient here for over 30 years....”
“Always a friendly welcome, efficient and punctual service and providing good advice. Highly...”
“Staff work very well as a team. They are friendly, listen carefully and...”
“Brilliant service as always. Best dental practice in Stockport.”
“All the staff I have seen are caring, sensitive and professional. Yet still...”
“I have been with the dental practice for many years and have always...”
“Friendly, professional and knowledgeable staff. Dr DeZoysa, Jill and Denise are absolute superstars....”
“Above and beyond, thank you.”
“Always been looked after well here, Amy is a brilliant dentist, and the staff are professional and friendly”
“Always good, friendly service from every member of staff. The dentist herself is gentle, knowledgeable and inspires confidence.”
“Friendly staff and helpful advice.”
“Always a great service and always friendly people.”
“Always so helpful, friendly and efficient! Top-class service in every way. Outstanding.”
“Staff are always friendly, and I have received great treatment every time from Amy.”
“As always, friendly, helpful and a pleasure to visit.”
“Great dental practice. I have been a patient here for over 30 years. I wouldn’t go anywhere else....”
“Always a friendly welcome, efficient and punctual service and providing good advice. Highly recommended.”
“Staff work very well as a team. They are friendly, listen carefully and are happy to help.”
“Brilliant service as always. Best dental practice in Stockport.”
“All the staff I have seen are caring, sensitive and professional. Yet still able to make the visit...”
“I have been with the dental practice for many years and have always been treated with kindness and...”
“Friendly, professional and knowledgeable staff. Dr DeZoysa, Jill and Denise are absolute superstars. They have worked really hard...”
